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Bacterial vs Fungal vs Viral Keratitis Explained

Written by the Mungale Eye Hospital team

Medically reviewed by Dr. Meeta Mungale, MBBS, MS (Ophthalmology), DNB · Fellowship in Cornea & Anterior Segment, L V Prasad Eye Institute, Hyderabad · Gujarat Medical Council Reg. No. G-39262 · Reviewed on 14 October 2026

Published 14 October 2026

Part of our guide: Corneal Ulcer & Keratitis: Symptoms & Treatment

Illustration: ophthalmologist and a lab technician reviewing a microscope slide in a clean eye hospital laboratory in Vadodara.

Keratitis means inflammation of the cornea, often caused by infection. Bacterial, fungal and viral keratitis can look similar at first, but they come from different germs and need different medicines. Using the wrong drop can make an infection worse, so finding the exact cause is a key part of treatment.

Why Does the Type Matter?

  • Antibiotics treat bacteria but not fungi or viruses
  • Antifungal drops are needed for fungal infection
  • Antiviral medicines are used for herpes keratitis
  • Steroid drops can worsen fungal and some viral infections
  • Choosing the right medicine early protects the cornea and vision.

    Bacterial Keratitis

    Common causes

    Contact lens overwear, sleeping in lenses, poor lens hygiene, eye injury and severe dry eye.

    Typical features

    Rapid onset of pain, redness, thick yellow or green discharge and a white or yellow spot on the cornea. It can worsen within a day or two.

    Treatment

    Intensive antibiotic drops, often every hour at first, then tapered as healing begins.

    Fungal Keratitis

    Common causes

    Injury from plant material, a twig, crop leaves, soil or vegetable matter. It is especially common in agricultural workers and in warm, humid climates. Overuse of steroid drops is another risk.

    Typical features

    Slower onset, a greyish-white spot with feathery or fluffy edges, and sometimes small satellite spots. Pain may seem less than the size of the ulcer suggests.

    Treatment

    Antifungal drops such as natamycin or voriconazole, often for several weeks. Some cases need oral medicines or surgery.

    Viral Keratitis

    Common causes

    Herpes simplex virus is the most common. Herpes zoster (shingles) can also affect the eye.

    Typical features

    Redness, watering, light sensitivity and blurred vision. On examination, the doctor may see a branching pattern called a dendritic ulcer. Episodes may recur, often with stress, fever or illness.

    Treatment

    Antiviral drops or tablets. Some patients need long-term preventive antiviral medicine to reduce recurrences.

    How Do Doctors Tell Them Apart?

    The doctor examines the eye with a slit lamp and dye. A corneal scraping may be sent for staining and culture to identify bacteria or fungi. In some cases, tests for viruses are added. History, such as contact lens use or plant injury, also gives important clues.

    Key Takeaways

  • Keratitis can be bacterial, fungal or viral.
  • Each type needs a specific medicine.
  • Plant injuries often cause fungal keratitis.
  • Contact lens misuse is a major cause of bacterial keratitis.
  • Never use steroid drops without an eye doctor's advice.
  • Final Thoughts

    Three different germs can cause very similar painful red eyes, which is why self-treatment is risky. Early diagnosis and targeted treatment give the cornea the best chance to heal clearly. For expert corneal care, you can consult Dr. Meeta Mungale, an ophthalmologist at Mungale Eye Hospital in Vadodara.

    Frequently Asked Questions

    Both bacterial and fungal keratitis are common in India. Fungal keratitis is seen more often in agricultural regions and after plant injuries. Bacterial keratitis is frequently linked to contact lens misuse in cities.

    Fungi grow deeper into the cornea and respond more slowly to medicines. Treatment often takes several weeks and needs close follow-up. Some severe cases need surgery, such as a corneal transplant, to control infection.

    Yes. The herpes virus can stay dormant in nerves and reactivate during stress, fever or illness. Some people need long-term antiviral tablets to reduce recurrences. Early treatment of each episode protects the cornea.

    Steroids can reduce inflammation but may worsen fungal and viral infections by weakening the eye's defences. Using them without an eye exam can turn a treatable infection into a severe one.

    It is a quick test where the doctor gently collects cells from the ulcer surface after numbing the eye. The sample is examined in the lab to identify the germ so the right medicine can be chosen.

    Infectious keratitis usually affects one eye. However, poor hygiene, shared towels or touching both eyes can spread some infections. Wash hands often and avoid touching the healthy eye.

    Sources and further reading

  • AAO: What is a corneal ulcer (keratitis)?
  • AAO: Contact lens-related eye infections
  • Reviewed by

    MBBS, MS (Ophthalmology), DNB · Fellowship in Cornea & Anterior Segment, L V Prasad Eye Institute, Hyderabad

    Gujarat Medical Council Reg. No. G-39262

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